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2 Oct 2010
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575 Memorial Drive
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(Book) "Informatics in Oral Medicine: Advanced Techniques in Clinical and Diagnostic Technologies”

Author(s)/Editor(s): Andriani Daskalaki (Max Planck Institute for Molecular Genetics, Germany)
Pages: 1-424 pp

Description : Advancing medical technologies are now developing cutting-edge computer applications useful to the field of oral studies.

Informatics in Oral Medicine: Advanced Techniques in Clinical and Diagnostic Technologies provides innovative research techniques on current technologies in the management of problems in oral health and medicine. A unique and comprehensive reference source, this enriched collection contains valuable computational tools and the latest applications in dental and oral research topics such as artificial mouths, laser melting, and dentist appointment management.

Preface: Informatics tools offer solutions to many problems in oral health clinic and research, but also face significant challenges, linking of data from the clinical diagnostic technologies. The field of bioinformatics will have several main areas of interest in oral medicine including the development of software and analysis tools for genomics and proteomics data related to oral tissues, in particular for the analysis of data from DNA arrays, mass spectrometry, and protein-protein and protein-DNA interactions in the analysis and interpretation of these data. Methodologies shall focus on methods from multivariate statistics, for example testing statistical hypotheses, cluster analysis and classification, and networks as well as functional annotation of sequence data.
The in silico analysis of complex biological processes, such as gene regulatory motifs, metabolic networks, and signal transduction pathways, will play an important role in the development of diseases, infections as well as oral tissue malformations. Specific efforts have to be made for the integration of databases and experimental data into the kinetic models, for example in order to test mutations or to validate drug targets for oral cancer.”
The aim of the book is to gain insight into technological advances in the field of oral health informatics. We aimed this book for the clinician, and the researcher in this evolving field.

Organization of the book
The book is roughly divided into 5 sections:
Section One : “Informatics tools in oral medical research” introduces the basic concepts in the use of computational tools in oral medical research. Chapter 1 deals with the development of “artificial mouths”. The need to develop instrumental techniques that reproduce mouth conditions is explained. In this chapter are presented the difficulties and advances in reproducing oral functions, such as mouth temperature, saliva, breathing and mastication. Chapter 2 is focused on proteomics applications by using mass spectrometry and protein microarrays in oral medicine. The emphasis of chapter 3 is on concepts from molecular biology, genetics, and traditional pathology to provide new insights into oral diseases, and the associated technologies to provide new diagnostic and prognostic information. Chapter 4 describes novel approaches to study regulation of neurotrophin expression and release from neurons by activity.
Section Two,Informatics tools in oral diagnostic technologies” serves as a comprehensive introduction to computational methods supporting oral diagnosis. Chapter 5 discusses the methods for assessing the complexity of oral plaque biofilms. Chapter 6 describes Human Papilloma Virus (HPV) detection and genotyping using the Luminex xMAP technology. Chapter 7 provides information related to Time Sequencing and Force Mapping with Integrated Electromyography to measure occlusal parameters.
Section Three3D-Visualization in oral medicine” includes 5 chapters. Chapter 8 deals with the description of selective laser melting in dentistry .Chapter 9 introduces techniques for the generation of 3D Finite Element Meshes of human organs. In chapter 10 the author describes the Finite Element Method (FEM), a widely applied mathematical model that permit us to know the biomechanical behaviour of the human mandible in various clinical situations under physiological and standardized trauma conditions. Chapter 11 gives an overview of the current literature regarding the present use of cone-beam computed tomography in the localization of impacted teeth for orthodontic purposes. Chapter 12 present different approaches for computer-assisted surgery (CAS) in dental implantology.
Section FourBioinformatics applications in bacterial identification” describes informatics tools and techniques related to oral bacteria identification. Chapter 13 describes a developed meta-analysis approach which helps to extract sets of genes related to oral infections and interaction networks by integrating and combining quantitative data using statistical approaches. Chapter 14 discuss the potential capability of modern molecular genetic technologies utilizing bioinformatics.
In Section FiveInformatics tools in the management of dental care”, Chapter 15 presents new innovative services in dentist appointment management.

The book “ Informatics in Oral Medicine: Advanced Techniques in Clinical and Diagnostic, Technologies” contains text information, but also a glossary of terms and definitions, contributions from international experts, in-depth analysis of issues, concepts, new trends, and advanced technologies in oral medicine. This edition focuses more directly and extensively than ever on applications of informatics in oral medicine. The diverse and comprehensive coverage of multiple disciplines in the field of oral health informatics in this book will contribute to a better understanding all topics, research, and discoveries in this evolving, significant field of study. I hope will make this book a helpful tool-not only for the student who needs an expert source of basic knowledge in oral health informatics, but also for the advanced researcher who needs clear, concise, and balanced information on which to conduct his research.
In shaping this book, I committed myself to making the textbook as useful as possible to students and advanced researchers coping with the demands of modern medical research. Thanks to a very hard-working advisory editorial board of scientists, excellent authors who fulfilled our invitations, and a very efficient publisher providing clear procedures and practices for a quality production, readers may now enjoy chapters on some of the major ideas that have concerned computing and its applications in oral medicine.
                                 Andriani Daskalaki
                                 Max Planck Institute, Berlin, Germany
Topics Covered  
·  CAD informatics tools
·  Clinical technologies
·  Dentist appointment management
·  Development of artificial mouths
·  Diagnostic technologies
·  HPV research
·  Informatics in oral medicine
·  Molecular disease mechanisms
·  Proteomics in dental research
·  Selective laser melting

Table of Contents & List of  International Contributors (16 Chapters)   (please Click on this Title to access the Site where you will find the Book’s Chapters) !
Important Note:  in that Site, each of the “Chapter’s Title” redirects you  to the chapter abstract and contributor information.

Author's/Editor's Bio
Andriani Daskalaki presently works in the field of molecular medicine and bioinformatics at the Max Planck Institute for Molecular Genetics in Berlin.

She completed her PhD in 2002 on working in the applications of photodynamic therapy in the area of oral medicine from the Free University of Berlin. She received a two-year DAAD scholarship (1996-1998) for her research in the field of PDT. Dr. Daskalaki received a MS in Medical Informatics from TFH Berlin with her work in “Development of a documentation software for robot-assisted intraoral operations” and a MS degree in bioinformatics with her work in “Variance analysis of multifactor models in gene expression experiments with application to the identification of genetic markers for hypertension.” She received a poster prize for her participation in the International Photodynamic Association Meeting in Nantes. She is the editor of the “Handbook of Research on Systems Biology Applications in Medicine” and has presented many oral presentations at national and international meetings. She is a founding member and committee member of the Greek Dental Laser Association. Her research interest areas include systems biology, PDT, and laser applications in dentistry.

BIOTECHNICA 2009
6-8 Oct 2009
Hanover
Germany
Visit the Conference Site

First e-Tendering Solution for German Healthcare Sector
08 Jan 2009

Hospitals and other public institutions, just like private companies, feel the growing importance of optimizing their sourcing processes and organizing their procurement more efficiently due to financial reasons. "eVergabe", developed by the Hessian software provider Healy Hudson, is the first “e-tendering solution” for the European healthcare sector and is already in use by four procurement associations.
Like many other public authorities, hospitals often have to carry out European wide tenders. Furthermore, they have to operate increasingly economical without letting the quality of their work suffer. Because of that, the three German procurement associations Comparatio Health GmbH, EKK eG and P.E.G. eG agreed on a joint business solution for their electronic tendering needs.
The Comparatio Health GmbH was founded at the end of 2006 as a joint service and procurement association of the Hannover Medical School and the university hospitals of Schleswig-Holstein, Magdeburg, Greifswald and Göttingen. Its goal is to optimize the sourcing process by means of the bundling of volumes and the joint tendering of products of the medical and general economic demand while cutting the costs at the same time. The idea turned out to be very successful: a binding negotiated volume of 130 Mio. EUR was announced just after the first business year. In addition, the procurement costs were reduced significantly. At the beginning of 2008, the university hospital Regensburg joined the cooperation.
The procurement association of municipal hospitals in the German Association of Cities (Einkaufsgemeinschaft Kommunaler Krankenhäuser eG im Deutschen Städtetag, EKK eG) already exists for more than ten years. It is organized as a cooperative association and acts non-commercial. With its help, the associated hospitals get ways and means to position themselves competitive. Principal task of the procurement association is to organize a collaborative and legally compliant purchase of articles for the hospital demands and the product standardization combined with it in order to achieve savings. Further services of a professional procurement management like process optimization, continuing education, knowledge management, evaluation and benchmarking meanwhile top the image off.
The PEG eG, too, supports hospitals for many years now where an efficient management is concerned. Besides negotiating attractive terms, competent consulting services and the highest possible delivery reliability are its main targets. The association possesses a high market transparency and improves the position of its members through its know-how in procurement, technical management and process management.
All in all, the three organizations represent 507 acute care hospitals with a total of over 160.000 beds. Therefore it was very important to choose an application that is capable of handling such great capacities. Due to successful tests and the broad experience of the developer, the parties involved finally decided to go for the solution of the Healy Hudson GmbH, making "eVergabe" the first e-tendering-solution for the healthcare sector in Germany.
"With eVergabe, all tenders of the members will be published on a central platform and free of charge. The autonomy of the individual procurement associations remains unchanged, since the system administers them as single clients", says Pascal Patronidis, Director Public Sector at Healy Hudson. "Nevertheless they benefit from the synergy effects, e.g. the editing of forms, the definition of contract specifications and the corresponding savings potential at tenders."
With the “e.log” Einkauf und Logistik GmbH, yet another corporation from the healthcare sector has decided to build up an electronic tendering platform with the help of Healy Hudson. “e.log” was founded in 2001 and has set itself the target of being an interface between hospitals and suppliers, optimizing the procurement processes between them. It attaches great importance to the standardization of processes and products.
The tendering and placing of contracts will be carried out without any media disruption and a lot more efficiency in the future. Through this, the highest possible advantages for both the patients as well as the hospitals can be achieved. The employees of e.log can look back on many years of experience in the market for one thing, but for another thing they can also fall back on the professional competence of the affiliated hospitals, which enables them to develop successful sourcing strategies.
One main advantage of the individual tendering solutions from Healy Hudson is the very high acceptance rate regarding its users due to the fact that nearly no technical premises are necessary. To start using the platform, the user only needs a standard PC and an internet browser. Furthermore, the whole sourcing process from the publication to the placing of contracts can be handled electronically without any media disruption.

For further information, please visit:
http://www.healy-hudson.com   (see the EN version)

Commissioned Study and Final Report on “eHealth in Action: Good Practice in European Countries”

Source: InfSo & Media News on Good eHealth Project
Feb 2009

“Good eHealth - Exchange of Good Practices in eHealth” - is a three-year study (2006-2008) funded under the former Modinis programme by the Directorate-General Information Society and Media. The commissioned Study covered 30 European countries for which validated information was available to the project by the end of November 2008. The Report reflects the situation of the cases at the date of delivery to the project by national correspondents during the time period 2006-2008.
The main objectives pursued along the Study are to:

  • identify good practices and their associated benefits
  • develop and implement proven approaches to wider dissemination and transfer real-life experiences
  • stimulate accelerated take-up of eHealth by addressing common implementation challenges and lessons learned

The Report presents the final outcome of research in the context of the “Good eHealth project”, and it was implemented in cooperation between “Deloitte-Belgium” and “empirica -Communication and Technology Research, Germany”.
The “Good eHealth” project is funded by the European Commission, DG Information Society and Media, ICT for Health Unit.

Download
eHealth in Action Good Practice in European Countries Report (.pdf, 2.280 KB).

For further information, please visit the project web site:  http://www.good-ehealth.org/

"Economic impact of interoperable electronic health records and ePrescription in Europe"

The study is carried out by "Empirica" for the European Commission, DG Information Society and Media, Unit H1: ICT for Health
Obs : the "EHR IMPACT" Study should be viewed as closely linking to the EC- Empirica Study "FINANCING eHEALTH"

Source: EHR IMPACT Study Web Site -  http://www.ehr-impact.eu/index.htm
15 May 2008

  • The "EHR IMPACT" Study has started in the 1st of January 2008, and its ending date is 31 December 2008.
  • Key dates relating to the EHR IMPACT work are as follows:  

May 2008:  The case study of the computerised clinical information system at the University Hospitals in Geneva (HUG) , Switzerland, was presented at the European Union Ministerial Conference on eHealth 2008 in Portorož, Slovenia. Findings from the "Financing eHealth" and EHR IMPACT studies were illustrated on the basis of HUGs experience. The discussion focused on insights of strategic eHealth investment decisions , as well as the costs and benefits associated with complex, interoperable electronic health record (EHR) systems. The presentation material is available on the EHR IMPACT Study website:  www.ehr-impact.eu.

April 2008: First findings of the EHR IMPACT study will be presented next month at the European Union Ministerial Conference on eHealth 2008 in Portorož, Slovenia. The case study of the computerised patient record system at the University Hospitals in Geneva, Switzerland will be used as an example to illustrate the benefits, as well as lessons learnt for future investments in interoperable EHR and ePrescribing systems. The session will be shared with the Financing eHealth study, which focuses on the investment aspects of eHealth.

March 2008: The EHR IMPACT study team currently finalised the conceptual framework of the study, developing and adapting the eHealth IMPACT methodology. The goal is the evaluation of the socio-economic impact of eHealth in the specific setting of interoperable electronic health record and ePrescribing systems. The first two evaluations have started. These are the computerised patient record system at the University Hospitals in Geneva, (Switzerland), and the Scottish Emergency Care Summary Programme, in the UK.

More updated and detailed information on this Study could be found at the Web Site : http://www.ehr-impact.eu/index.htm ,   or following the links:

NEST organises a scientific exchange on neurological diseases as ALS in April (Moscow)
14-16 Apr 2008
Moscow
Russia  
Visit the NEST Site

16th International Conference on Health Promoting Hospitals and Health Services
14-16 May 2008
Berlin
Germany
Visit the Conference Site

Industry agrees standardised interface for EPRs

Source: eHEALTH Europe
20 Nov 2007

After one year of negotiations - faster than expected - more than 30 health IT companies have agreed on a new standardised interface for electronic patient records (EPR). The agreement will make it easier for EPR-solutions of different vendors to share personal medical data.

The new interface was being developed under the umbrella of the intiative EPA NRW in the German federal state of North-Rhine Westfalia. Companies involved include, among others, Agfa Healthcare, Careon, CompuGroup, DocExpert, fliegel, IBM, ICW, Microsoft, Siemens and T-Systems.

Like other federal countries, Germany is moving towards a system of regional eHealth networks of different providers with a high demand for interoperability. The basic concept is to have, next to each other, hospital-owned case records, life-long web-based personal health records (PHR), and regional server-based records for managed care-scenarios. All these electronic patient record solutions of different kinds will have to share data. This means that both a standardised interface and semantic standards are needed. 
(read more...)

Free version of medavis DICOM Importer

Source: MEDICA.de
Date: 21 Sept 2007

"Medavis" released a free tool to import medical image data into PACS Archives
The international standard DICOM for medical image data has been implemented for several years, but in reality the data exchange between hospitals or private institutes often fails due to technical problems. Even though nowadays nearly all software solutions offer the possibility to write individual patient image data onto data carriers like CD or DVD, this in many cases fails due to the data not being accepted by the receiver´s system. This is why important information for treatment or specific diagnostic is often not accessable.
In order to create a smooth exchange of information in the future, medavis GmbH has developed a software that can be used intuitively and free of charge for non-commercial use.
With the help of medavis DICOM Importer, DICOM media, as well as many other formats, can be imported and saved into a PACS archive. Apart from the possibility of importing the entire data of a data carrier by the push of a single button you can also choose between importing an image series or just single images with the built in preview function. For improved report assessment the users have, within the image preview function, functions like Pan, Zoom, Window-Center, at their disposal. 
The free version can be used for non-commercial use without time limitation and may be freely copied. The current version can be found in the download area of www.dicomimporter.com

The DICOM Conformance Statement can be downloaded in the download area of the medavis GmbH under www.medavis.com

European Conference on eHealth 2007
11-12 Oct 2007
Oldenburg
Germany
For more information click here

First Health Card Connector

Source: MEDICA.de ( www.medica.de )
Date: 9 May, 2007

(Walldorf/Berlin) – The operation company for the introduction of the electronic health card in Germany received the first connector for licensing pursuant to the current specification 1.0 today: eHealth specialist InterComponentWare AG (ICW) and network equipper Cisco submitted their jointly developed health card connector "Cisco Healthcare Router" to gematik for provisional licensing.

With grant of the provisional license by gematik, the Cisco Healthcare Router can now be applied in all German electronic health card test regions. The rollout for connectors with the current 1.0 specification in offline mode is planned for June. This connector version now allows the use of modern Secure Interoperable Chipcard Terminals (SICCT) for the first time. These terminals are also provided for application with the final version of the health card. Presently, the test regions Saxony and Schleswig Holstein still use MKT+ card readers, which are directly connected to the physicians' PCs without a connector. Together with this connector, the new terminals provide a clearly higher degree of data integrity. (read more....)

ISPro and Mednovo agreed to cooperate

Source: eHealth News - EC
Date: 9 May, 2007

The ISPro GmbH, Germany, Hattingen, and MEDNOVO GmbH & Co. KG Medical Software Solutions, Germany, Berlin, agreed in April 2007 to cooperate in coupling the telemarketing platform jesaja.net and the picture and finding documentation system MediColor.
As point of this cooperation MediColor will provide hospitals examination data such as pictures, videos, measuring data or test results for the referring physician portal jesaja.net.
Read more... http://www.ehealthnews.eu/content/view/546/26/

IRC workshop focuses on legal aspects of international trade

A seminar addressing international licences, supply and sales contracts, organised within the framework of northern Germany's Innovation relay centre (IRC) and supported by the European Commission's Enterprise DG will take place in Teltow, Germany on 21 to 23 February. (more)

7th International Conference on Telemedicine

The 7th International Conference on Telemedicine will be held in Germany next year. The conference will take place in Regensburg under the patronage of the International Society of Telemedicine (ISfT) from September 22nd to 25th 2002. (more)

IPR at National Level

A resource of practical information on intellectual property and innovation in Germany. (link)

The Impact of Telematics on the Healthcare Sector

Trends in Health Telematics in the European Union

EC funded Research Projects

 

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